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NAD Publication
In this page are reported the patent, publications, oral communication and posters of the NAD project
Year 2011 Patent, Publications, oral communication and posters:
Patent:
Greek patent n. 20100100563
“Novel curcumin derivatives with improved physicochemical properties and surface-decorated Nanoliposomes (with the derivatives) with very high affinity for Amyloid-β1-42 peptide”
Inventors: Massimo Masserini, Sophia Antimisiaris, Nicotra Francesco, La Ferla Barbara, Cristiano Zona, Spyridon Mourtas, Anna Niarakis
Italian patent n. RM2011A000264
"Nuovi composti triciclici glicofusi, procedimento per la loro produzione e loro impiego quali ligandi dei peptidi β amiloidi (Aβ), 2011"
Inventors: Nicotra F., Masserini M., La Ferla B., Airoldi C., Cardona F., Sironi E.
Nanomedicine: Nanotechnology, Biology, and Medicine - NAD special edition:
Moghimi S.M.
Editorial- Bionanotechnologies for treatment and diagnosis of Alzheimer's disease
Nanomedicine: Nanotechnology, Biology, and Medicine 7 (2011) 515 – 518
Cristina Gabellieri, Heico Frima
Editorial - Nanomedicine in the European Commission policy for nanotechnology
Nanomedicine: Nanotechnology, Biology, and Medicine vol.7 (2011) 519 – 520
Brambilla D, Le Droumaguet B, Nicolas J, Hashemi SH, Wu LP, Moghimi SM, Couvreur P, Andrieux K.
Nanotechnologies for Alzheimer's disease: therapy, diagnosis and safety issues
Nanomedicine: Nanotechnology, Biology, and Medicine: 7 (2011) 521–540
M. Taylor, S. Moore, S. Mourtas, A. Niarakis, F. Re, C. Zona, B. La Ferla, F. Nicotra, M. Masserini, S. G. Antimisiaris, M. Gregori, D. Allsop
Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide
Nanomedicine: Nanotechnology, Biology, and Medicinevol. 7 (2011) 541–550
F. Re , I. Cambianica , C. Zona, S. Sesana, R. Rigolio, F. Nicotra, G.Forloni, A. Cagnotto, M. Salmona, M. Masserini, G. Sancini
Functionalization of liposomes with ApoE-derived peptides at different density affects cellular uptake and drug transport across a blood-brain barrier model
Nanomedicine: Nanotechnology, Biology, and Medicine- Vol.7 (2011) 551–559
E. Bereczki, F. Re, M. E. Masserini, B. Winblad, Jin Jing Pei
Liposomes functionalized with acidic lipids rescue Aβ-induced toxicity in murine neuroblastoma cells
Nanomedicine: Nanotechnology, Biology, and Medicine 7 (2011) 560–571
A. Skouras, S. Mourtas, E. Markoutsa, M.C. De Goltstein, C.Wallon, S. Catoen, S. G. Antimisiaris
Magnetoliposomes with high USPIO entrapping efficiency, stability and magnetic properties
Nanomedicine: Nanotechnology, Biology, and Medicine 7 (2011) 572–579
Other Publications:
Canovi M, Markoutsa E, Lazar AN, Pampalakis G, Clemente C, Re F, Sesana S, Masserini M, Salmona M, Duyckaerts C, Flores O, Gobbi M, Antimisiaris SG.
The binding affinity of anti-Aβ1-42 MAb-decorated nanoliposomes to Aβ1-42 peptides in vitro and to amyloid deposits in post-mortem tissue.
Biomaterials 2011 Aug;32(23):5489-97. Epub 2011 May 6.
Journal of Biotechnology 156 (2010) 338– 340B. Le Droumaguet, H. Souguir, D. Brambilla, R. Verpillot, J. Nicolas, M. Taverna, P. Couvreur, K. Andrieux
Selegiline-functionalized, PEGylated poly(alkyl cyanoacrylate) nanoparticles: Investigation of interaction with amyloid- peptide and surface reorganization
Int J Pharm. 2011 Sep 20;416(2):453-60. Epub 2011 Jan 18.
C. Airoldi a, C. Zonaa, E. Sironi, L. Colombob, M. Messa, D. Aurilia, M. Gregori, M. Masserini, M. Salmona, F. Nicotra, B. La Ferla
Curcumin derivatives as new ligands of Aβ peptides
J Biotechnol. 2010 Dec 20;156(4):317-24. Epub 2011 Jul 22
D. Brambilla, H. Souguir, J. Nicolas, N. Mackiewicz, R. Verpillot, B. Le Droumaguet, M. Taverna, P. Couvreur, K. Andrieux
Colloidal properties of biodegradable nanoparticles influence interaction with amyloid-Beta peptide
J Biotechnol. 2010 Dec 20;156(4):338-40. Epub 2011 Jul 22.
Zoia CP, Riva C, Isella V, Proserpio P, Terruzzi A, Arban S, Salerno D, Cassina V, Mantegazza F, Tremolizzo L, Ferrarese C.
Nonfibrillar Abeta1-42 Inhibits Glutamate Uptake and Phosphorylates p38 in Human Fibroblasts.
Alzheimer Dis Assoc Disord. 2011 Apr-Jun;25(2):164-72.
Markoutsa E, Pampalakis G, Niarakis A, Romero IA, Weksler B, Couraud PO, Antimisiaris SG.
Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line.
Eur J Pharm Biopharm. 2011 Feb;77(2):265-74. Epub 2010 Nov 29.
Mourtas S, Canovi M, Zona C, Aurilia D, Niarakis A, La Ferla B, Salmona M, Nicotra F, Gobbi M, Antimisiaris SG.
Curcumin-decorated nanoliposomes with very high affinity for amyloid-β1-42 peptide.
Biomaterials. 2011 Feb;32(6):1635-45. Epub 2010 Dec 4.
Airoldi C, Colombo L, Manzoni C, Sironi E, Natalello A, Doglia SM, Forloni G, Tagliavini F, Del Favero E, Cantù L, Nicotra F, Salmona M.
Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction.
Org Biomol Chem. 2011 Jan 21;9(2):463-72. Epub 2010 Nov 10.
Oral communication and poster:
NAD mini-symposium: Nanoparticle for Therapy and Diagnosis of Alzheimer Disease
Erika Sironi, C. Airoldi, F. Cardona, B, La Ferla, C. Zona, F. Nicotra
New Aß peptide ligands for the diagnosis and therapy of Alzheimer’s Disease
NAD mini-symposium- EuroNanoforum, Budapest, 30th May -1st June 2011
Hasna Ahyayauch, Michal Raab, Alicia Alonso, Igor Tvaroska, Massimo Masserini and Félix M. Goñi
Interaction of monomeric amyloid beta-protein (Aß-42) with anionic phospholipids: Experimental experiments
NAD mini-symposium - EuroNanoforum, Budapest, 30th May -1st June 2011
Michal Raab, Hasna Ahyayauch, Alicia Alonso, Igor Tvaroska, Massimo Masserini and Félix M. Goñi
Interaction of monomeric amyloid beta-protein (Aß-42) with anionic phospholipids: Simulation experiment
NAD mini-symposium - EuroNanoforum, Budapest, 30th May -1st June 2011
Spyridon Mourtas, Anna Niarakis, Eleni Markoutsa,Athanasios Skouras, Sophia Antimisiaris
Optimization of the click reaction on nanoliposome surface for preparation of various types of vesicles decorated with a curcumin-derivative
NAD mini-symposium - EuroNanoforum, Budapest, 30th May -1st June 2011
Mark Taylor
“Effect of curcumin-associated and lipid ligand functionalised nanoliposomes on aggregation of the Alzheimer’s Aß peptide”
NAD mini-symposium - EuroNanoforum, Budapest, 30th May -1st June 2011
Francesca Re, Ilaria Cambianica, Cristiano Zona, Alfredo Cagnotto, Silvia Sesana, Giulio Sancini, Massimo Masserini
ApoE-nanoliposomesfor transport of Ab1-42-ligands across the blood-brain barrier: a study in a model system.
NAD mini-symposium - EuroNanoforum, Budapest, 30th May -1st June 2011
A. Pakkanen, J. Rokka, O. Solin, M. Haaparanta, J.O. Rinne
In vivo PET imaging of amyloid plaques in experimental animals
NAD mini-symposium - EuroNanoforum, Budapest, 30th May -1st June 2011
Other communication and poster:
Dinnyés András
NANORÉSZECSKÉK AZ ALZHEIMER KÓR DIAGNOSZTIZÁLÁSÁRA ÉS KEZELÉSÉRE (NAD)
XII. Alzheimer-kór Konferencia Budapest, 2011. szeptember 22-24
E. Bereczki, F. Re, M.E. Masserini, B. Winblad, JJ Pei
Liposomes functionalized with acidic lipids rescue Aß induced toxicity in murine neuroblastoma cells
EuroNanoforum, Budapest, 30th May -1st June 2011
Benjamin Le Droumaguet
Functionalized PEGylated Poly(Alkyl Cyanoacrylate) Nanoparticles for Applications in Alzheimer’s disease
EuroNanoforum, Budapest, 30th May -1st June 2011
J. Nicolas
"Advanced Poly(alkyl cyanoacrylate) Nanoparticles for Cell Imaging and Against Alzheimer's Disease"
EuroNanoforum, Budapest, 30th May -1st June 2011
S. Mourtas, A. Niarakis, C. Zona, D. Aurilia, B. La Ferla, F. Nicotra, S. Antimisiaris
Click reaction on nanoliposome surface for preparation of various types of vesicles decorated with a curcumin-derivative
EuroNanoforum, Budapest, 30th May -1st June 2011
Francesco Nicotra, Francisco Cardona, Barbara La Ferla, Erika Sironi,Cristina Airoldi, Artur Silva
Glycofused tricycles as beta-amyloid peptide ligands for the diagnosis and therapy of Alzheimer’s Disease
EUROCARB 2011, 3-7 July 2011, Sorrento (NA), Italy.
Le Droumaguet B.; Nicolas J., Brambilla D., Zona C.; Nicotra F.; Canovi M.; Gobbi M.; Couvreur P.; K . Andrieux
PEGylated Poly(Alkyl Cyanoacrylate) Nanoparticles Functionalized by Click Chemistry for Applications in Alzheimer's Disease
3rd Pharmascifair, Prague, Czec Republic, 13-17 June2011.
D. Brambilla, R. Verpillot, M. Taverna, B. Le Droumaguet, J. Nicolas, J. Kóna, L. De Kimpe, M. Canovi, M. Gobbi, V. Nicolas, M. Salmona, W. Scheper, I. Tvaroška, P. Couvreur, K. Andrieux
Nanoparticles against Alzheimer’s disease: PEG PACA nanoparticles are able to link the Aß-peptide and influence its aggregation kinetic.
3rd Pharmascifair, Prague, Czec Republic, 13-17 June 2011.
S. Sesana, F. Re, I. Cambianica, A. Cagnotto, G. Sancini, M. Masserini
"Uptake of Nanoliposomes Functionalizated with ApoE-derived Peptide by Brain Capillary Endothelial Cells"
Nanomedicine Workshop -8th International Conference on Nanosciences And Nanotechnologies - 12-15 July 2011, Thessaloniki, Greece
K. Andrieux
Nanoparticles for brain drug delivery
NanoBioEurope, Cork, Ireland, 20-23 June 011
Francesco Nicotra, Barbara La Ferla, Cristina Airoldi, Erika Sironi, Francisco Cardona, Cristiano Zona.
Aß Peptide ligands for therapy and diagnosis of Alzheimer Disease
German-Austrian-French-Hungarian-Italian conference in organic and biomolecular chemistry 2011 (GAFHI 2011)
26th-29th May 2011, Goslar, Austria.
Gloria Galimberti, Elisa Conti, Maria Gregori, Fulvio DaRe, Marco Tironi, Massimo Masserini, Carlo Ferrarese
Binding of lipid-based nanoparticles to plasma Abeta: relevance for new therapeutic strategies in Alzheimer’s disease - Poster
VI Congresso Sindem Associazione Autonoma per le Demenze aderente a Sin - Milano 17 - 19 Marzo 2011
Gloria Galimberti, Elisa Conti, Maria Gregori, Fulvio DaRe, Marco Tironi, Massimo Masserini, Carlo Ferrarese
Binding of lipid-based nanoparticles to plasma Abeta: relevance for new therapeutic strategies in Alzheimer’s disease- Abstract
"VI Congresso Sindem Associazione Autonoma per le Demenze aderente a Sin Milano 17 - 19 Marzo 2011"
Pakkanen Anniina, Lopez-Picon FR, Rokka Johanna, Forloni Gianluigi, Salmona Mario, Solin Olof, Scheinin Mika Rinne Juha, Haaparanta Merja
Comparison of [11C]PIB binding in the brain of APP23 and APP/PSI transgenic mice
AD/PD 2011 - Barcelona Spain 9-13 March 2011
Year 2010 Patent, Publications, oral communication and posters:
Patent:
International patent n. PCT/IT2009/000251
“ Liposomes capable of effectively binding the beta-amyloid peptide”
Inventors: Prof. Massimo Masserini; Dr. Francesca Re; Dr. Mariasilvia Sesana
Publications:
Brambilla D, Verpillot R, Taverna M, De Kimpe L, Le Droumaguet B, Nicolas J, Canovi M, Gobbi M, Mantegazza F, Salmona M, Nicolas V, Scheper W, Couvreur P, Andrieux K.
New method based on capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) to monitor interaction between nanoparticles and the amyloid-β peptide.
Anal Chem. 2010 Dec 15;82(24):10083-9. Epub 2010 Nov 18.
Islam Hamad, Othman Al-Hanbali, A. Christy Hunter, Kenneth J. Rutt,†Thomas L. Andresen, and S. Moein Moghimi
Distinct Polymer Architecture Mediates Switching of Complement Activation Pathways at the Nanosphere - Serum Nanoparticle Engineering
ACS Nano. 2010 Nov 23;4(11):6629-38. Epub 2010 Oct 28.
M. Gregori; V. Cassina; D. Brogioli; D. Salerno; L. De Kimpe; W. Scheper; M. Masserini; F. Mantegazza
Stability of Abeta (1-42) peptide fibrils as consequence of environmental modifications
Eur Biophys J (2010) vol.39, pages 1613–1623
D. Brambilla, J. Nicolas, B. Le Droumaguet, K. Andrieux, V. Marsaud, P. O. Couraud and P.Couvreur
Design of fluorescently tagged poly(alkyl cyanoacrylate) nanoparticles for brain endothelial cells imaging.
Chemical Communication 2010, 46, 2602–2604.
F. Re, C. Airoldi, C. Zona, M. Masserini, B. La Ferla, N. Quattrocchi and F. Nicotra
Beta Amyloid Aggregation Inhibitors: Small Molecules as Candidate Drugs for Therapy of Alzheimer’s Disease
Current Medicinal Chemistry, 2010, Vol. 17, pages 2990-3006
Marco Gobbi, Francesca Re, Mara Canovi, Marten Beeg, Maria Gregori, Silvia Sesana, Sandro Sonnino, Doriano Brogioli, Claudia Musicanti, Paolo Gasco, Mario Salmona, Massimo Masserini
Lipid-based nanoparticles with high binding affinity for amyloid-β1-42 peptide
Biomaterials, Sept. 2010, Vol. 31 - Pages 6519-6529
Moghimi SM, Andersen AJ, Hashemi SH, Lettiero B, Ahmadvand D, Hunter AC, Andresen TL, Hamad I, Szebeni J.
Complement activation cascade triggered by PEG-PL engineered nanomedicines and carbon nanotubes: the challenges ahead
Journal of Controlled Release 146 (2010) 175–181
L. De Kimpe and W. Scheper
From Alpha to Omega with Abeta: Targeting the Multiple Molecular Appearances of the Pathogenic Peptide in Alzheimer’s Disease
Current Medicinal Chemistry, 2010, Vol. 17, No. 3, page 198-202
Oral communication and poster:
Pakkanen Anniina, Rokka Johanna, Lopez-Picon FR , Forloni Gianluigi, Salmona Mario, Solin Olof, Rinne Juha, Haaparanta Merja
Longitudinal evaluation of [11C]PIB binding in the brain of APP23 mice
Neuroscience 2010, San Diego, USA
D. Brambilla, R. Verpillot, L. De Kimpe, M. Taverna, B. Le Droumaguet, J. Nicolas, M. Canovi, M. Gobbi, M. Salmona, V. Nicolas, W. Scheper, P. Couvreur, K. Andrieux
NANOPARTICLES AGAINST ALZHEIMER’S DISEASE: PEG-PACA NANOPARTICLES ARE ABLE TO LINK THE Aß-PEPTIDE AND INFLUENCE ITS AGGREGATION KINETIC
14th International Biotechnology Symposium and Exhibition, 14-18 September 2010, Rimini, Italy.
C. Zona, B. La Ferla, C. Airoldi, D. Aurilia, E. Sironi, F. Nicotra et al
Design and synthesis of ligands and nanoparticles for therapy and diagnosis of Alzheimer’s Disease
14th International Biotechnology Symposium and Exhibition, 14-18 September 2010, Rimini, Italy.
F. Re, I. Cambianica, S. Sesana, A. Cagnotto, M. Salmona, M.Masserini, G. Sancini
Tat-1-liposomes to overcome the blood-brain barrier: an in vitro study
14th International Biotechnology Symposium and Exhibition, 14-18 September 2010, Rimini, Italy.
Francesca Re
Preparation and Characterization of Lipid-Based Nanoparticles Binding with High Affinity Amyloid-b1-42 Peptide
14th International Biotechnology Symposium and Exhibition, 14-18 September 2010, Rimini, Italy.
B. La Ferla, C. Zona, D. Aurilia, C. Musicanti, G. Riccio, G. Vanhoutte
Fluorinated molecules and molecular devices as MRI tools
14th International Biotechnology Symposium and Exhibition, 14-18 September 2010, Rimini, Italy.
D. Brambilla, R. Verpillot, L. De Kimpe, M. Taverna, B. Le Droumaguet, J. Nicolas, M. Canovi, M. Gobbi, M. Salmona, V. Nicolas, W. Scheper, P. Couvreur, K. Andrieux
Nanoparticles against Alzheimer’s disease: PEG PACA nanoparticles are able to link the Aß-peptide and influence its aggregation kinetic
2nd Conference Innovation in Drug Delivery, 3-6 October 2010, Aix en Provence, France.
Cardona F., La Ferla B., Sironi E., Airoldi C., Silva A., NicotraF.
Synthesis and NMR interaction studies of glycofused tricycles as beta-amyloid peptide ligands
XII Belgian Organic Synthesis Symposium, July 11-16, 2010, Namur, Belgium (Poster).
Canovi M., Stravalaci M., Beeg M., Re F. , Musicanti C., Gasco P., Forloni G., Salmona M., Masserini M. & Gobbi M.
In vitro characterization of nanoparticles functionalized for targeting Amyloid-beta 1-42 peptide.
7th FENS forum of European neuroscience - July 3-7, 2010 Amsterdam, The Netherlands - poster
G. Galimberti, A. J. Andersen, S. H. Hashemi, F. Re, Thomas L. Andresen, C.Ferrarese, M. Masserini and S. M. Moghimi
Regulation of Antibody-Mediated Activation of Alternative Pathway of Complement System by an Abeta-Binding Liposomes: Effect of Vesicular Curvature and Surface Charge Density
7th FENS- Forum European Neuroscience - July 3-7, 2010 - Amsterdam, The Netherland
La Ferla B., Cardona F., Sironi E., Airoldi C., Silva A., Nicotra F.
Glycofused polycycles as beta-amyloid peptide ligands
XII Congress-Scuola sulla Chimica dei Carboidrati, 20-23 June 2010, Pontignano- Italy
D. Brambilla, R. Verpillot, L. De Kimpe, M. Taverna, B. Le Droumaguet, J. Nicolas, M. Canovi, M. Gobbi, M. Salmona, V. Nicolas, W. Scheper, P. Couvreur, K. Andrieux
Nanoparticles against ALZHEIMER'S disease: PEG-PACA nanoparticles are able to link the Aβ-peptide and influence its aggregation kinetic
3rd European Conference for Clinical Nanomedicine, May 10-12, 2010, Basel, Switzerland
Sironi E., Airoldi C., Cardona F., La Ferla B., Colombo L., Manzoni C., Salmona M., Nicotra F
NMR characterization of the interaction between Aβ peptide and small ligands for the development of the new anti- Alzheimer’s drugs
Italian-Spanish Joint Workshop, April 22, 2010, Milan, Italy (Oral communication).
C. Zona, B. La Ferla, C. Airoldi, D. Aurilia, E. Sironi, F. Nicotra
Design and synthesis of ligands and nanoparticles for therapy and diagnosis of Alzheimer’s Disease
Italian-Spanish Joint Workshop project 2008-3175, April 22, 2010, Milan, Italy (Oral communication)
R. Verpillot, D. Brambilla, K. Andrieux, B. Le Droumaguet, J. Nicolas, M. Canovi, M. Gobbi, M. Salmona, V. Nicolas, P. Couvreur, M. Taverna
Interaction between PEG-PACA nanoparticles and amyloid peptide highlighted by Capillary Electrophoresis.
Microscale separation, 21-25 Mars 2010, Prague, République Tchèque. (poster presentation)
D. Brambilla, R. Verpillot, M. Taverna, B. Le Droumaguet, J. Nicolas, M. Canovi, M. Gobbi, M. Salmona, V. Nicolas, P. Couvreur, K. Andrieux
Nanoparticles against ALZHEIMER'S disease: PEG-PACA nanoparticles are able to link the Aβ-peptide and influence its aggregation kinetic
7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 8-11 March 2010, Malta, Valetta.
Year 2009 Publications, oral communication and posters:
Publications:
Alina J. Andersen, S. Hossein Hashemi, Thomas L. Andresen,A. Christy Hunter, and S. Moein Moghimi
“Complement: Alive and Kicking Nanomedicines”
J. Biomed. Nanotechnol. 2009, Vol. 5, No 6, page 364-372.
D. Brogioli, D. Salerno, V. Cassina, F. Mantegazza
"Nanoparticle characterization by using tilted laser microscopy:back scattering measurement in near field"
Optic Express, Vol. 17, No. 18, pp 15431-15448, Aug. 2009
Barbara La Ferla, Cristiano Zona; Francesco Nicotra
“Easy Silica Gel Supported Desymmetrization of PEG”
Synlett 2009, n° 14- New York
Spyridon Mourtas, Georgios P. A. Michanetzis, Yannis F. Missirlis and Sophia G. Antimisiaris
“Haemolytic Activity of Liposomes: Effect of Vesicle Size, Lipid Concentration and Polyethylene Glycol-Lipid or Arsonolipid Incorporation”
Journal of Biomedical Nanotechnology Vol. 5, 1–7, 2009
D. Brogioli, D. Salerno, V. Cassina, S. Sacanna, A. P. Philipse, F.Croccolo, and F. Mantegazza
“Characterization of anisotropic nanoparticles by using depolarized dynamic light scattering in the near field”
2 February 2009 / Vol. 17, No. 3 / OPTICS EXPRESS
Oral communication and poster:
Julien Nicolas, Benjamin Le Droumaguet, Davide Brambilla, Karine Andrieux, Patrick Couvreur
“Advanced Poly(alkyl cyanoacrylate) Nanoparticles for Drug Delivery Purposes”
11th Pacific Polymer Conference, Cairns, Australia, Dec. 6-10, 2009.
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C. Zona
Design and synthesis of nanoparticles for imaging and therapy of ALZHEIMER's disease
Day of the Department of Biotechnology and Biosciences 2009,11th Nov. 2009, University of Milano-Bicocca, Milan- Italy (poster)
J. Nicolas
Nanoparticules de poly(alkyl cyanoacrylate) : fonctionnalisation, imagerie intracellulaire et interactions avec le peptide amyloïde Abeta
23ème Colloque du Biotechnocentre, Tour, France, October 21-22, 2010
B. Le Droumaguet, J. Nicolas, J. Roisin, K. Andrieux, P. Couveur
Synthesis of highly functionalized nanoparticles based on POLY(ALKYL CYANOACRYLATE) by means of click chemistry
17th International Symposium on Microencapsulation, Nagoya, Japan, September 29 - October 1, 2009
D. Brambilla, R. Verpillot, J. Nicolas, M. Taverna, P. Couvreur, K. Andrieux
Nanoparticles for the therapy of ALZHEIMER'S disease: ability of Pegylated poly(alkyl cyanoacrylate) nanoparticles to link to the Aβ peptide 1-42 and to influence its aggregation kinetic
17th International Symposium on Microencapsulation, Nagoya, Japan, September 29 - October 1, 2009
Airoldi C., Sironi E., Colombo L., Manzoni C., Salmona M., Nicotra F.
Abeta peptide – small molecule interaction studies as a tool for the development of new anti-Alzheimer’s drugs
14th International Biotechnology Symposium and Exhibition, Biotechnology for the Sustainability of Human Society, September 14-18, 2009, Rimini, Italy
D. Brambilla, R. Verpillot, L. De Kimpe, M. Taverna, B. Le Droumaguet, J. Nicolas, M. Canovi, M. Gobbi, M. Salmona, V. Nicolas, W. Scheper, P. Couvreur, K. Andrieux
Nanoparticles against ALZHEIMER'S disease: PEG-PACA nanoparticles are able to link the Aβ-peptide and influence its aggregation kinetic
14th International Biotechnology Symposium and Exhibition, 14-18 September 2009, Rimini, Italy.
D. Brambilla, R. Verpillot, L. De Kimpe, M. Taverna, B. Le Droumaguet, J. Nicolas, M. Canovi, M. Gobbi, M. Salmona, V. Nicolas, W. Scheper, P. Couvreur, K. Andrieux
Nanoparticles against ALZHEIMER'S disease: PEG-PACA nanoparticles are able to link the Aβ-peptide and influence its aggregation kinetic
15th International Pharmaceutical Technology Symposium , 13-15 septembre 2009, Antalya, Turkey (invited communications)
Pakkanen A, Rokka J, Lopez F, Forloni G, Salmona M, Solin O, Rinne JO, Haaparanta M.
[11C]PIB Shows Increased Binding in the Brain of the Transgenic APP23 Mice Even With Modest Specific Radioactivity
World Molecular Imaging Congress, Kyoto , Japan, 2-10 September, 2009
Brambilla D., nicolas J., Couvreur P., Andrieux K
“Nanoparticles for therapy of Alzheimer’s Disease: PEG-PACA NPs ability to link the Aβ peptide 1-42 and to influence its aggregation kinetic “
presented in :
1- Journées de Printemps Société de circulation et métabolisme du cerveau, NANCY,
April 2-3 2009: poster
2- Annual meeting of the society for the studies of blood brain barrier interfaces -
April 24-25 2009, Strasbourg: poster
3- PharmScifair, Nice 7-12 june 2009: oral communication
4- EuroNanoMedicine, 28-30 Sept. 2009, Bled, Slovenia : poster
B. Le Droumaguet, J. Nicolas, P. Couvreur, K. Andrieux
“PEG-PACA nanoparticles functionalized by “click chemistry” for β-amyloid peptide targeting”
presented in:
1- Annual meeting of the society for the studies of blood brain barrier interfaces (S.E.I.S.C.) -
April 24-25 2009, Strasbourg: poster
2- PharmScifair, Nice 7-12 june 2009: oral communication.
3- EuroNanoMedicine, 28-30 Sept. 2009, Bled, Slovenia : oral communication
Julien Nicolas, Fethi Bensaid, Didier Desmaële, Karine Andrieux and Patrick Couveur
“Highly Functionalized, Stealth, Poly(alkyl cyanoacrylate) Nanoparticles by “Click” Chemistry”
Controlled release society, Copenhagen, Danmark, July 18-22, 2009
Davide Brambilla, Romain Verpillot, Julien Nicolas, Myriam Taverna, Patrick Couvreur, Karine Andrieux
“Synthesis of higly functionalized nanoparticles based on poly(alkyl cyanoacrylate) by menas of click chemistry”
17th International Symposium on Microencapsulation, Nagoya, Japan, Sept.29 - Oct. 1, 2009
Francesca Re, Marco Gobbi, Mario Salmona, Massimo Masserini
“The NAD project: Nanoparticles for therapy and diagnosis of Alzheimer’s Disease - Preliminary results with nanoliposomes.”
Transaction Conference_Copenaghen_July 2009
Massimo Masserini
“Nanoparticles for therapy and diagnosis of Alzheimer Disease (NAD)”
Euronanoforum- Prague- Czech Republic- June 2009
Cristiano Zona, Barbara La Ferla, Francesco Nicotra
“Design and synthesis of monomers for the generation of functionalized nanoparticles”
Gordon Research Conference: Carbohydrate, 14-19 June 2009, Tilton, New Hampshire, U.S.A
Cristiano Zona; Francesco Nicotra, Barbara La Ferla
“Design and Synthesys of Liposome Nano particles for the Diagnosys and Therapy of Alzheimer’s Disease”
Conf.:Biotech:org Forte dei Marmi (Lu) Italy_2009
Francesca Re, Massimo Masserini, Maria Gregori, Valeria Cassina, Matteo Stravalaci, Mario Salmona, Marco Gobbi
“The NAD project: Nanoparticles for therapy and diagnosis of Alzheimer’s Disease - Preliminary results with nanoliposomes”
Euronanoforum- Prague Czech Republic June 2009
Nikokolista Nomikou, Eleni Markousta, Sophia G. Antimisiaris
“Evaluation of integrity of GM1- or PA- incorporating nanosized liposomes: effect of amount incorporated and lipid composition”
Conference in Athens - Greece - May 2009
Nikokolista Nomikou, Eleni Markousta, Sophia G. Antimisiaris
“Characterisation of GM1-and PA- containing nanosized liposomes”
5th intenartional greek biotecnology forum
Year 2008 Publications and posters
Doriano Brogioli, Fabrizio Croccolo, Valeria Cassina, Domenico Salerno, Francesco Mantegazza
“Nano-particle characterization by using Exposure Time Dependent Spectrum and scattering in the near field methods: how to get fast dynamics with low-speed CCD camera”
8 December 2008 / Vol. 16, No. 25 / OPTICS EXPRESS
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NAD Publications